The Epidemiological Survey of Intestinal Parasite Among Primary School Students in Shahrood City Semnan Province and Comparative Study About Efficacy of Metronidazole and Quinacrine in Giardiasis

SUMMARY For detem1inating the prevalence of pathogenic protozoa and helminths in the Shahrood city and comparative between efficacy of metronidazole and Quinacrine in 1372-1373.from I 6649 students, 1043 students selected randomly and stool examination was done by direct and concentration with fonnol ether methods. Among the pathogenic protozoa prevalence of Giardia lamblia Emamoeba histolytica were respectively 21 and I percent. Relative percent of helminths as H. nana oxyur, Dicrocoelium and Trichocephalea were respectively 2 % . 1 % and O .1. This investigation showed that 55 % of cases with giardiasis has not any clinical manifestation. From 216 cases with giardiasis 133 cases selected randomly for comparison of therapeutic effect only 98 students were collected second sample for evaluation of drugs effect. 49 cases with metroniadazole to Metroniadazole and 49 cases with quinacrine were been treated. One case to Metronidazole (2 % ) and three cases to quinacrine ( 6 % ) showed resistance this difference is not statistically significant.